It should be fine in a 110 with a healthy specimen, plenty of live rock, water changes, and not over feeding. Just wanted you to be conscientious. Groupers tend to be hardy, but are BIG eaters, poopers. Ideally small fish 2-3" range would be a good start. The bacteria in your tank will have to adjust with each new addition/ extra feeding. Putting too much bioload on your tank too quickly is a very, very common way of killing fish in the beginning. It sounds like you are putting a lot of thought into the tank, which is great. You will have a much more rewarding experience.

Why no clowns for the anemones? It's good to choose the anemone, let it settle before getting clowns for it. But after that, the anemone will benefit from the hosting.