I have one now, and I noticed a few differences. The best pro I can come up with is initial weight. The big aquarium I have it much easier to handle then a comparably sized glass. The second pro is that it seems to magnify the fish making them appear bigger.
If you’re anything like me you sometimes go 3 days too long between scrapings. The plastic scrapers just do not seem to do as good of a job scraping as the metal blades used on glass. My aquarium is horribly scratched in the worst places. The kid grabbed the float the other day and I guess it had a piece of sand or 20 on the Velcro pad. And she cleaned the center of the front of my aquarium, in circles.
In short, no, I will never have an Acrylic aquarium again.