Can you post pictures? Also, what is it eating? Is it a species specific tank or community? How many other Pompanos?

Sounds like the lumps are tumors of some sort which I believe are not treatable. Not sure about the spots...what do the bumps look like in color? If they are white and red then they are most likely Aeromonas or Columnaris and can be treated.

I'm just throwing things out there to try to help in some way...I really have no idea what you have. Pics would help so that we can all research.