The problem you have is that with that 45 degree run, you have way too many places for air to become trapped. Running an airline down there might not "find" the right place.
In addition: 1" drains will NOT drain enough for your returns. I have 2" drains on mine, and it's set up such that 1 of the 2 drains can be plugged, and the other can handle the 1750gph return. However, 2" handles 4X the volume of 1".
First thing I'd try is to see if you can get at least a foot of so of straight down run before turning 45 degrees. You might also TRY stepping up your drain size to 1.5" or 2" - at least then your only restriction is the 1" hole in the tank.
One last comment: you should NEVER plumb relying on all of your drains to be working. One WILL become plugged, and as well, over time your drains will get calcium growths slowing them down.
Bill
215g FOWLR... and anemones, GSP, gorgonians... carp, that isn't FO!
"I killed my first SW Fish in 1971..."