I have lost 2 so far and the others are looking effected too. I don't have the ability to do such a large waterchange, I only have 2 5 gal buckets. I will mix up as soon as I can. they are a drop in the bucket to my 125 gal tank... My clown and my dansels are looking bad. The clown has lots of white spots and my damsels are loosing color. my yellow tang and lion fish and starfish look normal.