I know a few people that dose B-ionic part 1 in the morning and part 2 at night for reasons listed above...personally I swear by B-ionic and I use both parts back to back without any adverse effects. Similarly I have used Kent 2 part and two little fishies (I think c-balance?) dosed the same as B-ionic with-out ill effects.

I think the main idea is to let the Alk part soak in as much as possible before adding the calcium. I usually wait 10-20 minutes before dosing the second part of the solution.