Yeah, depending on the configuration of the stand (open top or not). My 110 has a corner overflow, bottom drilled. I mounted my tank on an old credenza, that has an 1-3/4" thick oak top :o Man was that tough to drill :angry In addition, my stand has two braces inside, one of which had to be drilled, and they were 1-1/4" thick :mellow Check it out first, and if you need to drill it, make sure you get the right size hole saw for the plumbing to fit through with ample space for fittings, and dont buy the cheap $15 saw, you'll regret it when it breaks :(