To be honest, my fuge probably has more to do with my water quality than the Bio-Balls.
When I put this system together I just put in some of everything that worked for me so well in my 125g and added to it. The way I figure it, all of these things contribute in some way to the chemical/ecological balance and I doubt that any of us fully understand how they interact as a "System". I do have a very large wet/dry filled with Bio-Balls and mechanical filtration (floss). Also have a large fuge with a DSB, and a DSB in all the tanks, plus a VERY generous supply of live rock, lots of sump space, and an aggresive skimmer. Bio-load is reasonable, but not heavy, I feed as little as I can get away with, and do 20% water changes every two weeks.
Richard's peleted Charcoal bed fuge is intriguing! I have considerd changing my small frag tank into one of these?





