Joe's Juice works great when you can see and dose the anemone.
My problem is after one dies off 3-4+ little bitty aptasia show up around the base of the dead aptasia. I believe they were there all along and just living in the shadow of the big one that I was able to kill.
I think you can be successful with Joe's if you start early and stay after them for about a week. Once they take hold it is near impossible to get rid of them without a natural predator like copperband or peppermint shrimp.
Dave
djbeck10 (at) gmail.com