This has been very well explained by Ping. Anaerobic bacteria grows where there is very little oxygen, the anoxic zone. That is why a DSB is required to be deep. Earlier it was mentioned that the size of the grain doesnt matter, in my opinion it does. That is why sugar fine sand is recomended, because the grains are so small and tighly pressed together that they do a better job at blocking oxygen into the dsb. Normally a deeper sand bed when grains are larger.
DSB work, they are great in my opinion. Just like Ping mentions, I also only recomended only if it is required for some critters. In the earlier days, the days before skimmers, you couldnt go without one as it was the main source of nutrient export. Thanks to skimmers, more often than not we can afford to go without one. Increase the flow, eliminate dead zones, and turn up the skimmer is the most popular way these days.
BTW, live rock is also great for establishing anaerobic bacteria. It grows very deep inside the rock. The great thing is that it also has alot of surface area where aerobic bacteria grows.
Jerry
Trying to get back in the hobby... Will be seting up my 75g rr soon