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sharkboy
Sat, 30th Sep 2006, 11:07 AM
Does anyone have any of this stuff? None of the lfs have this in stock. Thanks!
Art 669-8521

JimD
Sat, 30th Sep 2006, 11:14 AM
Have you checked with CB pets?

sharkboy
Sat, 30th Sep 2006, 11:17 AM
No...it is a little far for me. I'm out by Sea World. Hoping to find something closer.

GaryP
Tue, 3rd Oct 2006, 02:10 PM
I'm probably going to end up with some Dutch hitman from Salifert knocking on my door, but don't waste your time or money. It will wipe out 99% of them, but the other 1% will just come back and have enough resistance to it that it will be useless in the future. That was my experience with it. Adding a predator is the way to go with controlling these guys.

If you are dertermined to treat. Try finding some PraziPro at the LFS. I think its the same thing, just cheaper.

witecap4u
Tue, 3rd Oct 2006, 08:16 PM
It took me 3 tries to wipe all of mine out, but it worked 100%. The key is to do it double strenght then dose regular every couple days for a week or two afterwards. As with any medication or what ever, remove any carbon and turn off your skimmers. BTW, you can order it online and get it in a couple days.

CSeel

GaryP
Thu, 5th Oct 2006, 11:02 PM
It took me 3 tries to wipe all of mine out, but it worked 100%. The key is to do it double strenght then dose regular every couple days for a week or two afterwards.
That is an example of what the drug folks call a "sub-lethal dose response." I had a somewhat heated discussion about this with the owner of Salifert (Habib) at MACNA. Unfortunately I tried the product early on before a lot of other people had worked out the idea of double dosing and all I managed to do was make my FWs resistant.

This is also why we have so many antibiotic resistant bacteria out there. Lots of people use sub-lethal doese of antibiotics as a preventative rather then as a cure for an actual outbreak of disease.

Bill S
Fri, 6th Oct 2006, 09:36 AM
That's why it's so important when taking antibiotics to take the entire dose. Also, if a Dr. prescribes an antibiotic just to get you out of the office (for like the flu or a cold) - and there are plently that do that - it 1) doesn't work and 2) accomplishes further development of resistant bacteria.

In college, the professor I was working under and I were showing how easy it is for the resistance to jump between bacterial species or transfer resistance to other bacteria. Oh, and to develop new strains of resistant bacteria, all we did was irradiate a bunch of bacteria with low level radiation (damage their DNA & RNA) and then expose them to lethal amounts of the antibiotics. The ones that survived were resistant. We had some that were resistant to over 10 kinds of antibiotics.

Ross
Fri, 6th Oct 2006, 11:14 AM
We were just talking about that in bio, pretty neat stuff. My professor said theres some types of bacteria out there now that can't be killed with antibiotics.

Bill S
Fri, 6th Oct 2006, 11:32 AM
The drug companies have a very difficult time keeping up wth evolution. That's why there's such a SPECIFIC list of antibiotic order of use. They "save" the good/new ones for the most resistant cases.

Bacteria develop "plasmids" which are nodules of DNA or RNA that can be transmitted from one cell to another. These can carry codes for restriction enzymes that destroy the antibiotic. Pretty cool. Oh, and this is from my memory from 30 years ago. I can't believe I actually remember this stuff.

safeuerwehr
Fri, 6th Oct 2006, 11:33 AM
good example of this is the MRSA (methicillin resistant Staphylococcus aureus) virus, which is resistant to most commonly used antibiotics....

Bill S
Fri, 6th Oct 2006, 12:19 PM
Staph is a bacterium, not a virus...

hobogato
Fri, 6th Oct 2006, 01:29 PM
The drug companies have a very difficult time keeping up wth evolution. That's why there's such a SPECIFIC list of antibiotic order of use. They "save" the good/new ones for the most resistant cases.

Bacteria develop "plasmids" which are nodules of DNA or RNA that can be transmitted from one cell to another. These can carry codes for restriction enzymes that destroy the antibiotic. Pretty cool. Oh, and this is from my memory from 30 years ago. I can't believe I actually remember this stuff.

you must have had a good bio teacher :)

GaryP
Sun, 8th Oct 2006, 05:00 AM
Well....

Bstreep has a masters in Biochem. Not exactly high school level biology stuff.